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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
F2 - coagulation factor II
Alias:
Cf2
FII
Cf-2
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一种依赖于维生素K的糖蛋白凝血因子,在血液凝固和止血过程中起着重要作用。编码的蛋白质是一种无活性的酶原,通过凝血因子Xa进行酶切形成一种活性丝氨酸蛋白酶,将可溶性的纤维蛋白原转化为不溶性的纤维蛋白凝块。大多数缺乏编码蛋白质的小鼠在胚胎阶段由于卵黄囊血管缺陷而死亡,而罕见的幸存者会在出生后第一天因出血而死亡。[由RefSeq,2015年4月提供]
Related ID:
NCBI:14061
ENSEMBL:ENSMUSG00000027249
UNIPROT:P19221
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
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Reference
14061
3
14
24058 bp
70.27
8
13
F2 Genetics information (-)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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