Enables 1-phosphatidylinositol-4-phosphate 5-kinase activity. Predicted to be involved in several processes, including 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process; negative regulation of 1-phosphatidylinositol-4-phosphate 5-kinase activity; and positive regulation of autophagosome assembly. Located in endoplasmic reticulum. Orthologous to human PIP4K2C (phosphatidylinositol-5-phosphate 4-kinase type 2 gamma). [provided by Alliance of Genome Resources, Apr 2022]