Atp6v0a4 - ATPase, H+ transporting, lysosomal V0 subunit A4

Predicted to enable ATPase binding activity and P-type proton-exporting transporter activity. Acts upstream of or within proton transmembrane transport. Located in apical plasma membrane; brush border; and endosome. Part of vacuolar proton-transporting V-type ATPase complex. Is expressed in several structures, including alimentary system; genitourinary system; musculoskeletal system; respiratory system; and sensory organ. Used to study renal tubular acidosis. Human ortholog(s) of this gene implicated in renal tubular acidosis. Orthologous to human ATP6V0A4 (ATPase H+ transporting V0 subunit a4). [provided by Alliance of Genome Resources, Apr 2022]