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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Mecom - MDS1 and EVI1 complex locus
Alias:
Jbo
Mds
Evi1
Mds1
Evi-1
Prdm3
Znfpr1b1
Mds1-Evi1
D630039M04Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活DNA结合转录激活因子活性,特异性为RNA聚合酶II;RNA聚合酶II顺式调控区域序列特异性DNA结合活性;以及组蛋白甲基转移酶活性(特异性H3-K9)。参与造血干细胞增殖;异染色质组织;以及负调控DNA模板的转录。在几个过程的上游或内部发挥作用,包括动物器官发育;胚胎肢芽形态发生;以及棕色脂肪细胞分化的正向调控。位于细胞核中。在几个结构中表达,包括消化系统;大脑;生殖泌尿系统;呼吸系统;和感觉器官。用于研究中耳炎。该基因的人类同源物与我的髓系瘤有关。与人类MECOM(MDS1和EVI1复合物位点)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:14013
ENSEMBL:ENSMUSG00000027684
UNIPROT:P14404
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
14013
21
16
558493 bp
138.10
17
10
Mecom Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Type
Name
MGI
Strain of Origin
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References Literature
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IF
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