人类

CRP - C-reactive Protein

Alias:
PTX1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质属于五肽素家族,还包括血清淀粉样P成分蛋白质和五肽素3。五肽素通过与其补体启动模式识别分子交流,参与补体的激活和放大,但也通过招募补体调节剂参与补体调节。编码的蛋白质具有依赖钙的配体结合结构域,具有独特的扁平β-果冻结构。它以五聚体形式在循环中存在,或以不溶性的单体形式存在于组织中。根据其识别外来病原体和宿主受损细胞的能力,并与血液中的体液和细胞效应系统相互作用,从而启动它们的消除,参与几种宿主防御相关功能。因此,在组织损伤、感染或其他炎症刺激的急性期反应期间,血浆中该蛋白质的水平显著增加。编码蛋白质的升高表达与严重急性呼吸综合症冠状病毒2感染有关。[RefSeq,2020年8月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
4
2
2301 bp
25.04
13
--
6
13

CRP Genetics information (-)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Comparison
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