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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
CRP - C-reactive Protein
Alias:
PTX1
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
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References Literature
这个基因编码的蛋白质属于五肽素家族,还包括血清淀粉样P成分蛋白质和五肽素3。五肽素通过与其补体启动模式识别分子交流,参与补体的激活和放大,但也通过招募补体调节剂参与补体调节。编码的蛋白质具有依赖钙的配体结合结构域,具有独特的扁平β-果冻结构。它以五聚体形式在循环中存在,或以不溶性的单体形式存在于组织中。根据其识别外来病原体和宿主受损细胞的能力,并与血液中的体液和细胞效应系统相互作用,从而启动它们的消除,参与几种宿主防御相关功能。因此,在组织损伤、感染或其他炎症刺激的急性期反应期间,血浆中该蛋白质的水平显著增加。编码蛋白质的升高表达与严重急性呼吸综合症冠状病毒2感染有关。[RefSeq,2020年8月提供]
Related ID:
NCBI:1401
ENSEMBL:ENSG00000132693
HGNC:2367
UNIPROT:P02741
OMIM:123260
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
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1401
4
2
2301 bp
25.04
13
--
6
13
CRP Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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No data available
Transcripts & Proteins
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Transcript
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* This data comes from NCBI.
Gene Expression
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Name
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Status
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References Literature
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