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中文人类
CRKL - CRK Like Proto-oncogene, Adaptor Protein
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这个基因编码一个包含SH2和SH3结构域的蛋白激酶，已被证明可以激活RAS和JUN激酶信号通路，并以RAS依赖的方式转化成纤维细胞。它是BCR-ABL酪氨酸激酶的底物，在BCR-ABL诱导的成纤维细胞转化中发挥作用，可能具有致癌性。[由RefSeq，2009年1月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CRKL Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
