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中文人类
CRK - CRK Proto-oncogene, Adaptor Protein
Alias:
p38
CRKII
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这个基因编码一个接头蛋白家族的成员，该成员与几个酪氨酸磷酸化蛋白质结合。这个基因的产物具有几个SH2和SH3结构域（src同源结构域），并参与几个信号传导途径，通过SH2-磷酸酪氨酸相互作用在酪氨酸激酶附近招募细胞质蛋白质。这个蛋白质的N端SH2结构域作为转化的正调节子，而C端的SH3结构域作为转化的负调节子。已经描述了编码具有不同生物活性的不同异构体的两种替代转录本。[由RefSeq，2008年7月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CRK Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
