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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Ercc3 - excision repair cross-complementing rodent repair deficiency, complementation group 3
Alias:
XPB
Ercc-3
BTF2 p89
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有ATP水解活性,并特异性结合启动子染色质。在UV保护及RNA聚合酶I启动子的转录延长过程中发挥上游作用。预测位于核质中。预测是RNA聚合酶II转录调节复合物、核苷酸切除修复因子3复合物和转录起始复合物的一部分。在包括大脑、眼睛、肝脏、口腔区域上皮和牙齿在内的几个结构中表达。用于研究B组色素性皮肤病。该基因的人类同源物与肺癌、光敏感硫酯营养不良2、硫酯营养不良、色素性皮肤病和B组色素性皮肤病有关。与人类ERCC3(ERCC切除修复3,TFIIH核心复合物螺旋酶亚基)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:13872
ENSEMBL:ENSMUSG00000024382
UNIPROT:P49135
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
13872
2
15
29850 bp
89.13
7
2
Ercc3 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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* This data comes from NCBI.
Gene Expression
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Name
MGI
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