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Ercc3 - excision repair cross-complementing rodent repair deficiency, complementation group 3

Alias:
XPB
Ercc-3
BTF2 p89
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有ATP水解活性,并特异性结合启动子染色质。在UV保护及RNA聚合酶I启动子的转录延长过程中发挥上游作用。预测位于核质中。预测是RNA聚合酶II转录调节复合物、核苷酸切除修复因子3复合物和转录起始复合物的一部分。在包括大脑、眼睛、肝脏、口腔区域上皮和牙齿在内的几个结构中表达。用于研究B组色素性皮肤病。该基因的人类同源物与肺癌、光敏感硫酯营养不良2、硫酯营养不良、色素性皮肤病和B组色素性皮肤病有关。与人类ERCC3(ERCC切除修复3,TFIIH核心复合物螺旋酶亚基)正交。[由基因组资源联盟,2022年4月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
2
15
29850 bp
89.13
7
2

Ercc3 Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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