Ercc1 - excision repair cross-complementing rodent repair deficiency, complementation group 1

这个句子很长，我将为您提取关键信息并翻译成中文。 1. Enables TFIID-class transcription factor complex binding activity and promoter-specific chromatin binding activity. 激活TFIID类转录因子复合物的结合活性和启动子特异性的染色质结合活性。 2. Involved in positive regulation of t-circle formation and t-circle formation. 参与正向调节t-环的形成和t-环的形成。 3. Acts upstream of or within several processes, including DNA metabolic process; UV protection; and gamete generation. 在包括DNA代谢过程、紫外线保护和生殖细胞生成等多个过程的上游或内部发挥作用。 4. Predicted to be located in chromosome, telomeric region and nucleoplasm. 预测位于染色体、端粒区和核质中。 5. Predicted to be part of ERCC4-ERCC1 complex and nucleotide-excision repair factor 1 complex. 预测是ERCC4-ERCC1复合物和核苷酸切除修复因子1复合物的一部分。 6. Is expressed in brain; cerebral cortex; and telencephalon. 在大脑、大脑皮层和端脑中表达。 7. Used to study XFE progeroid syndrome. 用于研究XFE早老症综合征。 8. Human ortholog(s) of this gene implicated in several diseases, including bone cancer (multiple); carcinoma (multiple); cerebrooculofacioskeletal syndrome 4; hematologic cancer (multiple); and transient cerebral ischemia. 这个基因的人类同源物与多种疾病有关，包括骨癌（多种）、癌（多种）、脑眼面骨骼综合症4、血液癌（多种）和短暂性脑缺血。 9. Orthologous to human ERCC1 (ERCC excision repair 1, endonuclease non-catalytic subunit). 与人类ERCC1（ERCC切除修复1，核酸内切酶非催化亚基）正交。 以上信息是根据Alliance of Genome Resources, Apr 2022提供的数据翻译的。