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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Erbb4 - erb-b2 receptor tyrosine kinase 4
Alias:
Her4
c-erbB-4
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活蛋白质酪氨酸激酶活性。参与几个过程,包括乳腺发育;神经系统发育;以及氮化合物代谢过程的正向调节。在几个过程的上游或内部发挥作用,包括对表皮生长因子刺激的细胞反应;肽酪氨酸自磷酸化;以及凋亡过程的调节。位于GABA能突触和谷氨酸能突触中。是突触后密度膜的集成组件。是突触前膜的集成组件。在几个结构中表达,包括大脑;早期概念期;胚胎外胚层;心和乳腺原基。这个基因的人类同源物与肌营养不良性侧索硬化19型;结直肠癌;食管鳞状细胞癌;肝细胞癌;和肺腺癌有关。与人类ERBB4(erb-b2受体酪氨酸激酶4)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:13869
ENSEMBL:ENSMUSG00000062209
UNIPROT:Q61527
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
13869
8
27
1076694 bp
146.85
12
19
Erbb4 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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