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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Eps8 - epidermal growth factor receptor pathway substrate 8
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活肌动蛋白结合活性和小GTP酶结合活性。参与几个过程,包括Rac蛋白信号传导;肌动蛋白丝组织;和末梢肌动蛋白丝帽。在几个过程的上游或内部发挥作用,包括肌动蛋白细胞骨架重组;乙醇的行为反应;和细胞对白血病抑制因子的反应。位于几个细胞组件中,包括刷状缘;ruffle膜;和纤毛尖端。NMDA选择性谷氨酸受体复合物的一部分。在几个结构中表达,包括肾上腺;消化系统;骨;脑;和肾单位。这个基因的人类同源物涉及常染色体隐性非综合征性耳聋102。与人类EPS8(表皮生长因子受体途径底物8)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:13860
ENSEMBL:ENSMUSG00000015766
UNIPROT:Q08509
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
13860
12
21
172021 bp
91.74
6
28
Eps8 Genetics information (-)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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