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中文小鼠
Eif2ak3 - eukaryotic translation initiation factor 2 alpha kinase 3
Alias:
Pek
Perk
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这个基因编码的蛋白质能够对真核细胞翻译起始因子2的α亚基进行磷酸化，导致其失活，从而快速降低翻译起始速率并抑制全球蛋白质合成。这个蛋白质被认为可以调节线粒体功能。它是一种位于内质网（ER）的I型膜蛋白，当内质网受到错误折叠的蛋白质引起的压力时，它会受到诱导。人类中类似基因的突变与Wolcott-Rallison综合症有关。[RefSeq, 2015年9月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Eif2ak3 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
