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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Eif2s1 - eukaryotic translation initiation factor 2, subunit 1 alpha
Alias:
35kDa
Eif2a
eIF2alpha
0910001O23Rik
2410026C18Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能够使核糖体结合活性和翻译起始因子活性。参与几个过程,包括细胞对氨基酸饥饿的响应;对应激反应的翻译起始的负调控;和应激颗粒组装。在蛋白质自磷酸化、对应激反应的翻译起始调控和翻译的上游或内部起作用。位于细胞质应激颗粒和核中。在突触中活跃。在几个结构中表达,包括脑室层;颌;鼻子;眶蝶;和胸腺原基。这个基因的人类同源物与阿尔茨海默病有关。与人类的EIF2S1(真核翻译起始因子2亚基α)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:13665
ENSEMBL:ENSMUSG00000021116
UNIPROT:Q6ZWX6
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
13665
1
8
24939 bp
36.11
3
13
Eif2s1 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
Length(nt)
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* This data comes from NCBI.
Gene Expression
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Name
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IF
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