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中文人类
CLDN7 - Claudin 7
Alias:
CLDN-7
CEPTRL2
CPETRL2
Hs.84359
claudin-1
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这个基因编码一个claudin家族的成员。Claudins是整合膜蛋白，是紧密连接链的组成部分。紧密连接链作为物理屏障，防止溶质和水分自由通过上皮或内皮细胞片之间的胞间空间。它们还在维持细胞极性和信号传导方面发挥关键作用。这个基因在不同类型的恶性肿瘤中的表达差异已经观察到，包括乳腺癌、卵巢癌、肝细胞癌、尿路上皮肿瘤、前列腺癌、肺癌、头颈部癌症、甲状腺癌等。已经发现了编码不同异型的替代剪接转录变异体。[RefSeq提供，2010年5月]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
CLDN7 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
Related Drugs
Name
CAS Number
Status
Phase
Link
References Literature
Title
PMID
Journal
Year
IF
