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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Egr1 - early growth response 1
Alias:
egr
TIS8
Zenk
Egr-1
NGFIA
Zfp-6
ETR103
Krox-1
Krox24
NGF1-A
NGFI-A
Zif268
Krox-24
A530045N19Rik
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活DNA结合转录激活因子活性,特异性结合RNA聚合酶II,并调节RNA聚合酶II转录调控区的DNA结合活性。参与多个过程,包括细胞对伽马辐射的响应;基因表达调控;以及激素生物合成过程的调控。在多个过程的上游或内部发挥作用,包括BMP信号通路;RNA聚合酶II的转录调控;以及骨骼肌细胞分化。位于细胞核中。在多个结构中表达,包括中枢神经系统;胚胎间充质;眼睛;生殖泌尿系统;以及颌。用于研究骨髓增生异常综合症。该基因的人类同源物与哮喘有关。与人类EGR1(早期生长反应1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:13653
ENSEMBL:ENSMUSG00000038418
UNIPROT:P08046
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
13653
1
2
3750 bp
56.59
12
21
Egr1 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Type
Name
MGI
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