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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Edn2 - endothelin 2
Alias:
VIC
ET-2
PPET2
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码内皮素家族肽成员。编码的前原蛋白经历蛋白水解过程生成一种强大的血管收缩肽。这个基因在胃肠道中丰富表达,在视网膜疾病和损伤中的光感受器细胞中强烈诱导表达,并且在青光眼的早期阶段由小胶质细胞和中性粒细胞产生。缺乏编码的蛋白质的小鼠表现出严重的生长迟缓、低体温和幼年致死。[RefSeq, 2016年2月提供]
Related ID:
NCBI:13615
ENSEMBL:ENSMUSG00000028635
UNIPROT:P22389
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
13615
1
5
6155 bp
19.54
8
4
Edn2 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Acting
Regulation
Detail
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Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
References Literature
Title
PMID
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Year
IF
No Data Found!
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