Log In|Sign Up
中文小鼠
Edn1 - endothelin 1
Alias:
ET-1
PPET1
preproET
Favorite
这个基因编码内皮素家族肽成员。编码的前原蛋白在分泌到血管内皮细胞之前经过蛋白水解处理生成肽。成熟的肽具有多种生物学活性，如血管收缩、细胞增殖、激素释放刺激和中枢神经系统活动的调节。缺乏编码蛋白的小鼠在出生时表现出致死性，并伴有颅面部和心血管系统多种缺陷，这是由于在早期胚胎发生过程中颅骨和心脏神经嵴细胞模式的中断所导致的。[RefSeq，2016年2月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Edn1 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
