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中文小鼠
S1pr1 - sphingosine-1-phosphate receptor 1
Alias:
S1p
Edg1
Lpb1
S1p1
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这个基因编码一个与溶血磷脂鞘氨醇1-磷酸结合的G蛋白偶联受体。该基因产物在内皮细胞中发挥作用，并涉及血管和心脏发育。这个受体在T和B淋巴细胞中高度表达，并在T细胞和B细胞从外周淋巴器官输出中发挥作用。这个蛋白质被外源性免疫抑制剂FTY720结合并下调，FTY720在人类多发性硬化症的小鼠疾病模型中进行了研究。[由RefSeq，2010年1月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
S1pr1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
