Atn1 - atrophin 1

Enables toxin activity; transcription coactivator activity; and transcription corepressor activity. Involved in cell migration and maintenance of cell polarity. Acts upstream of or within several processes, including determination of adult lifespan; male gonad development; and response to food. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and integumental system. Human ortholog(s) of this gene implicated in dentatorubral-pallidoluysian atrophy and schizophrenia. Orthologous to human ATN1 (atrophin 1). [provided by Alliance of Genome Resources, Apr 2022]