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Dnmt3b - DNA methyltransferase 3B

Alias:
MmuIIIB
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这是两个相关基因中的一个,这两个基因编码新的DNA甲基转移酶,负责在胚胎中建立DNA甲基化模式。这个基因的功能丧失会导致严重的发育缺陷和生存能力丧失。人类相关基因的突变导致免疫缺陷-着丝粒不稳定-面部异常(ICF)综合征。这个基因的假基因位于染色体2的同一区域中相邻的这个基因附近。已经观察到了编码多种异构体的可变剪接转录变异体。[由RefSeq,2012年11月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
23
20
38319 bp
97.23
16
20

Dnmt3b Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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