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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Twist2 - twist basic helix-loop-helix transcription factor 2
Alias:
Dermo1
bHLHa39
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活DNA结合转录因子活性;染色质结合活性;以及蛋白质结构域特异性结合活性。参与负调控转录,基于DNA模板。在几个过程的上游或内部发挥作用,包括面部形态发生;负调控细胞分化;以及负调控大分子代谢过程。是转录调节复合物的一部分。在几个结构中表达,包括消化系统;鳃弓;胚胎间充质;生殖泌尿系统;以及表皮系统。该基因的人类同源物涉及Barber-Say综合征;巨舌症综合征;以及焦点性皮肤发育不良。与人类TWIST2(twist家族bHLH转录因子2)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:13345
ENSEMBL:ENSMUSG00000007805
UNIPROT:Q9D030
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
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Reference
13345
1
2
46574 bp
18.14
8
6
Twist2 Genetics information (+)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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