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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Ddb1 - damage specific DNA binding protein 1
Alias:
127kDa
p127-Ddb1
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Description
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有多种预测功能,包括WD40重复结构域结合活性;Cullin家族蛋白质结合活性;以及受损DNA结合活性。参与细胞蛋白质代谢过程;糖异生作用的正向调节;以及生物钟调节。在Wnt信号通路的上游或内部发挥作用,并负向调节细胞凋亡过程。预测位于细胞质和核质中。预测是Cul4A-环指E3泛素连接酶复合物和Cul4B-环指E3泛素连接酶复合物的一部分。预测在核仁和双链断裂部位活跃。在包括肝脏;肺;耳囊;精母细胞;和脾脏在内的几个结构中表达。与人类的DDB1(损伤特异性DNA结合蛋白1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:13194
ENSEMBL:ENSMUSG00000024740
UNIPROT:Q3U1J4
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
13194
2
28
24226 bp
126.85
4
13
Ddb1 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Type
Name
MGI
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References Literature
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IF
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