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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Daxx - Fas death domain-associated protein
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有组蛋白结合活性和转录共激活子活性。参与核小体组装;通过RNA聚合酶II正向调控转录;以及蛋白质定位到染色质上。在几个过程的上游或内部发挥作用,包括凋亡信号通路;DNA模板的转录负调控;以及凋亡过程的调控。位于PML体和细胞质中。与异染色质共定位。在几个结构中表达,包括大脑;生殖泌尿系统;心脏;血淋巴样系统腺体;和肝脏。这个基因的人类同源物与胰岛细胞肿瘤和卵巢上皮癌有关。与人类的DAXX(死亡域关联蛋白)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:13163
ENSEMBL:ENSMUSG00000002307
UNIPROT:O35613
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
13163
5
8
6186 bp
81.49
10
17
Daxx Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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