Cyp2j6 - cytochrome P450, family 2, subfamily j, polypeptide 6

Enables arachidonic acid epoxygenase activity. Predicted to be involved in several processes, including negative regulation of collagen biosynthetic process; negative regulation of peroxisome proliferator activated receptor signaling pathway; and unsaturated fatty acid metabolic process. Located in endoplasmic reticulum. Is expressed in several structures, including alimentary system; integumental system; metanephros; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in hypertension (multiple); myocardial infarction; and renal fibrosis. Orthologous to human CYP2J2 (cytochrome P450 family 2 subfamily J member 2). [provided by Alliance of Genome Resources, Apr 2022]