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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
ADH7 - Alcohol Dehydrogenase 7 (class IV), Mu Or Sigma Polypeptide
Alias:
ADH4
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码IV类乙醇脱氢酶7μ或σ亚基,属于乙醇脱氢酶家族成员。这个家族的成员代谢各种底物,包括乙醇、视黄醇、其他脂肪醇、羟基固醇和脂质过氧化产物。这个基因编码的酶在乙醇氧化中效率低下,但作为视黄醇脱氢酶的活性最高;因此它可能参与视黄酸合成的过程,视黄酸是一种对细胞分化重要的激素。这个基因在胃中的表达比肝脏丰富得多,这与已知的其他基因家族成员不同。选择性剪接导致多个转录变异体。[RefSeq,2009年10月提供]
Related ID:
NCBI:131
ENSEMBL:ENSG00000196344
HGNC:256
UNIPROT:P40394
OMIM:600086
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
131
2
9
23080 bp
41.48
19
--
3
16
ADH7 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
Mutations
No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
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Interactions
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Acting
Regulation
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Mechanism
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Reference
Score
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Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
Related Drugs
Name
CAS Number
Status
Phase
Link
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
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