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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Cybb - cytochrome b-245, beta polypeptide
Alias:
Cgd
Cyd
Nox2
gp91-1
gp91phox
CGD91-phox
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个异源二聚膜离子转运蛋白的重链成分,该转运蛋白由重链和轻链组成。这个转运蛋白介导将电子从烟酰胺腺嘌呤二核苷酸磷酸(NADPH)转移到氧气,产生超氧化物。这个反应在天生免疫反应中对病原体很重要。然而,编码蛋白的活性增加也会导致产生反应性氧物质,导致氧化应激并可能损伤组织。另一方面,人类中相关基因的功能丧失导致慢性肉芽肿性疾病。替代剪接导致多个转录变异体,尽管其中一些变异体的全长性质尚未确定。[由RefSeq,2013年5月提供]
Related ID:
NCBI:13058
ENSEMBL:ENSMUSG00000015340
UNIPROT:Q61093
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
13058
2
13
52513 bp
65.31
11
13
Cybb Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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Transcript
Length(nt)
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* This data comes from NCBI.
Gene Expression
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IF
No Data Found!
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