小鼠

Cybb - cytochrome b-245, beta polypeptide

Alias:
Cgd
Cyd
Nox2
gp91-1
gp91phox
CGD91-phox
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个异源二聚膜离子转运蛋白的重链成分,该转运蛋白由重链和轻链组成。这个转运蛋白介导将电子从烟酰胺腺嘌呤二核苷酸磷酸(NADPH)转移到氧气,产生超氧化物。这个反应在天生免疫反应中对病原体很重要。然而,编码蛋白的活性增加也会导致产生反应性氧物质,导致氧化应激并可能损伤组织。另一方面,人类中相关基因的功能丧失导致慢性肉芽肿性疾病。替代剪接导致多个转录变异体,尽管其中一些变异体的全长性质尚未确定。[由RefSeq,2013年5月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
2
13
52513 bp
65.31
11
13

Cybb Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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