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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Cyba - cytochrome b-245, alpha polypeptide
Alias:
b558
nmf333
p22phox
p22-phox
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能够实现SH3结构域结合活性;电子转移活性;和蛋白质异二聚化活性。预测对产生超氧阴离子的NAD(P)H氧化酶活性有贡献。参与先天免疫反应。在粘液分泌的正调控中起到上游或内部作用;活性氧物种代谢过程;以及调控序列钙离子释放到细胞质中。位于内体。是NADPH氧化酶复合物的一部分。在多个结构中表达,包括生殖泌尿系统;血细胞系统;内耳;肢芽;和肝脏。这个基因的人类同源物与动脉疾病(多种);哮喘;慢性阻塞性肺病;和吞噬细胞杀菌功能缺陷(多种)有关。与人类CYBA(细胞色素b-245α链)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:13057
ENSEMBL:ENSMUSG00000006519
UNIPROT:Q61462
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
13057
2
6
8170 bp
20.75
8
9
Cyba Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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