小鼠

Ctss - cathepsin S

Alias:
Cats
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码半胱氨酸蛋白酶的肽酶C1(木瓜蛋白酶)家族的成员。可变剪接产生多个转录变异体,它们编码在蛋白水解过程中生成的成熟蛋白质产物。这种酶在炎症过程中由抗原呈递细胞分泌,并通过激活G蛋白偶联受体引发疼痛和瘙痒。这个基因的纯合敲除小鼠表现出伤口愈合受损,在胰腺癌模型中肿瘤生成减少,以及在重症肌无力模型中病理变化减少。[RefSeq,2015年8月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
3
8
29620 bp
38.48
12
11

Ctss Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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