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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Ctss - cathepsin S
Alias:
Cats
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码半胱氨酸蛋白酶的肽酶C1(木瓜蛋白酶)家族的成员。可变剪接产生多个转录变异体,它们编码在蛋白水解过程中生成的成熟蛋白质产物。这种酶在炎症过程中由抗原呈递细胞分泌,并通过激活G蛋白偶联受体引发疼痛和瘙痒。这个基因的纯合敲除小鼠表现出伤口愈合受损,在胰腺癌模型中肿瘤生成减少,以及在重症肌无力模型中病理变化减少。[RefSeq,2015年8月提供]
Related ID:
NCBI:13040
ENSEMBL:ENSMUSG00000038642
UNIPROT:O70370
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
13040
3
8
29620 bp
38.48
12
11
Ctss Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
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