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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Ctsk - cathepsin K
Alias:
catK
Ms10q
MMS10-Q
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码一个位于胱氨酸蛋白酶的cathepsin家族成员,在破骨细胞中高度表达,并参与骨胶原和其他基质蛋白的降解。编码的前原原蛋白经历蛋白水解加工,生成成熟的、具有功能的酶。缺乏编码蛋白的小鼠表现出毛糠状营养不良的特征,如骨密度增加和骨畸形,随着年龄的增长逐渐变得更加明显。[RefSeq,2016年1月提供]
Related ID:
NCBI:13038
ENSEMBL:ENSMUSG00000028111
UNIPROT:P55097
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
13038
1
8
10178 bp
36.89
15
10
Ctsk Genetics information (+)
GRCm39
Sequence Homology
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* This data comes from NCBI.
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