小鼠

Ctsh - cathepsin H

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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码半胱氨酸蛋白酶的肽酶C1(木瓜蛋白酶)家族的成员。可变剪接产生多个转录子变异体,其中至少一个编码前原蛋白,该前原蛋白在蛋白水解过程中被加工成多个蛋白质产物。这些产物包括组织蛋白酶H的迷你链、重链和轻链。在大鼠和人类中,这三个链可以结合形成成熟的酶,该酶具有氨基肽酶和内肽酶的活性。该基因的纯合性敲除小鼠表现出肺表面活性剂处理受损和胰腺癌症模型中的肿瘤生成减少。该基因在基因组中已经发现了多个假基因。[RefSeq,2015年8月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
3
12
21829 bp
37.17
6
5

Ctsh Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
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