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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Ctsc - cathepsin C
Alias:
CatC
DPP1
DPPI
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码半胱氨酸蛋白酶的肽酶C1(木瓜蛋白酶)家族的成员。可变剪接产生多个转录子变异体,其中至少一个编码前原蛋白,该前原蛋白在蛋白水解过程中被加工成多个蛋白质产物。这些产物包括二肽肽基肽酶1轻链、重链和排除域链,它们共同组成四聚同源酶的一个亚基。这种酶具有氨基二肽酶活性,可能在炎症过程中参与粒细胞的激活。这个基因的纯合性敲除小鼠表现出粒细胞激活受损,并在脓毒症模型中增强生存能力。[RefSeq,2015年8月提供]
Related ID:
NCBI:13032
ENSEMBL:ENSMUSG00000030560
UNIPROT:P97821
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
13032
5
4
32851 bp
52.38
6
11
Ctsc Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
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No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Cell-specific RNA expression
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Interactions
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Type
Name
MGI
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References Literature
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