小鼠

Ctsb - cathepsin B

Alias:
CB
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码肽酶C1家族的一员,并预先生成前蛋白,然后通过蛋白水解过程生成多个蛋白质产物。这些产物包括组织蛋白酶B轻链和重链,它们可以二聚化生成酶的双链形式。这种酶是一种具有内肽酶和外肽酶活性的溶酶体半胱氨酸蛋白酶,可能在蛋白质周转中发挥作用。这个基因的纯合性敲除小鼠在胰腺炎后胰腺损伤减少,并在肝脏损伤模型中肝细胞凋亡减少。这个基因的假基因已经在基因组中被发现。[由RefSeq,2015年8月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
2
10
23462 bp
37.28
5
10

Ctsb Genetics information (+)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
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