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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
TAF8 - TATA-box Binding Protein Associated Factor 8
Alias:
II
TAF
TBN
NEDMLHB
TAFII43
TAFII-43
TAF(II)43
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码几种TATA结合蛋白(TBP)相关因子(TAFs)之一,这些因子是通用转录因子TFIID的组成部分。TFIID识别许多基因的核心启动子,并组装一个包含RNA聚合酶II和其他起始因子的转录起始复合物。这个基因编码的蛋白质含有H4样组蛋白折叠结构域,并与TFIID的几个亚基相互作用,包括TBP和组蛋白折叠蛋白TAF10。已经描述了可变剪接的转录本变异体,但它们的生物学有效性尚未确定。[RefSeq,2008年7月提供]
Related ID:
NCBI:129685
ENSEMBL:ENSG00000137413
HGNC:17300
UNIPROT:Q7Z7C8
OMIM:609514
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
129685
10
9
36939 bp
34.26
19
3
6
13
TAF8 Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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Transcripts & Proteins
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* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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References Literature
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