Home
Toolbox
Resource
Workflow
Tutorials
Citations
Downloads
Mutation Al-Predictor Flow
Gene-to-Mutation Flow
News & Insights
Genetic Encyclopedia
Frontiers
Industry Insights
Case Studies
About Us
About the Site
Contact Us
Private Policy
User Agreement
COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
Log In
|
Sign Up
中文
小鼠
Crk - v-crk avian sarcoma virus CT10 oncogene homolog
Alias:
p38
Crk3
Crko
Crk-I
c-Crk
Crk-II
CrkIII
Crk-III
Create a favorites folder
Cancel
Confirm
Add To Favorites
Select a favorites
Description
New favorites >>
Cancel
Confirm
Favorite
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因是一个适配器蛋白家族的成员,该家族在响应细胞外刺激(如生长和分化因子)的情况下调节信号传导复合体的形成。蛋白质-蛋白质相互作用通过SH2结构域和SH3结构域发生,SH2结构域结合磷酸化的酪氨酸残基,SH3结构域结合富含脯氨酸的肽基序。这些相互作用促进效应蛋白的招募和激活,以调节细胞迁移、粘附和增殖。在鼠中,该蛋白对胚胎发育是必需的。已经描述了编码具有不同生物活性的不同异构体的可变剪接转录本。[由RefSeq,2013年3月提供]
Related ID:
NCBI:12928
ENSEMBL:ENSMUSG00000017776
UNIPROT:Q64010
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
12928
5
3
29235 bp
33.81
6
24
Crk Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Sequence
Comparison
Al agent
Tutorials
Back to top