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中文小鼠
Crh - corticotropin releasing hormone
Alias:
CRF
Gm1347
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这个基因编码促皮质素释放因子家族的一员，前原蛋白在蛋白水解过程中被加工成成熟的蛋白质产物。这个蛋白质产物是一种神经肽激素，能够与促皮质素释放激素受体（CRHR1和CRHR2）结合，刺激垂体腺释放肾上腺皮质激素以应对压力。编码的蛋白质还可能调节血管生成和炎症。这个基因的纯合子敲除小鼠皮质酮水平降低，而这些小鼠的后代在围生期死亡。[RefSeq, 2015年8月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Crh Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
