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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Atf6b - activating transcription factor 6 beta
Alias:
Crebl1
Creb-rp
ATF6beta
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能够使DNA结合的转录因子活性增强,特异性针对RNA聚合酶II,并能够与RNA聚合酶II的顺式调控区域序列特异性结合。预测能够促进DNA结合的转录激活子活性,特异性针对RNA聚合酶II。预测参与内质网未折叠蛋白应答;负调控ATF6介导的未折叠蛋白应答;以及响应内质网应激时从RNA聚合酶II启动子正调控转录。预测在响应未折叠蛋白的应答上游或内部发挥作用。预测位于内质网膜上。预测是RNA聚合酶II转录调节物和蛋白质-DNA复合物的一部分。预测在细胞核中活跃。在包括消化系统;中枢神经系统;生殖泌尿系统;皮肤和感觉器官在内的几个结构中表达。与人类的ATF6B(激活转录因子6β)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:12915
ENSEMBL:ENSMUSG00000015461
UNIPROT:O35451
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
12915
1
18
7929 bp
Unknown
5
7
Atf6b Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
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* This data comes from NCBI.
Gene Expression
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Name
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