小鼠

Cpe - carboxypeptidase E

Alias:
CPH
fat
Cph1
Cph-1
NF-alpha1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
该基因编码羧肽酶E,一种在内分泌和神经内分泌细胞的分泌颗粒中发现的激素原加工外肽酶。编码的前原原蛋白经历蛋白水解加工,生成成熟的、具有功能的酶,该酶切割蛋白质底物的C-末端碱性残基。这个基因中的错义突变负责一种名为“肥胖小鼠”的小鼠模型中的肥胖表型。缺乏这个基因功能产物的小鼠表现出多种肽激素如胰岛素原、强啡肽原、神经降压素、黑色素浓缩激素和阿片黑色素皮质激素加工过程的受损。[由RefSeq,2016年1月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
1
9
100568 bp
53.26
9
11

Cpe Genetics information (-)

GRCm39

Sequence Homology

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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