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中文小鼠
Col1a1 - collagen, type I, alpha 1
Alias:
Cola1
Mov13
Cola-1
Mov-13
Col1a-1
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这个基因编码形成原纤维的I型胶原的α-1亚基，I型胶原是骨骼、皮肤和肌腱细胞外基质中最丰富的蛋白质。编码的蛋白质与α-2亚基结合，形成异源三聚型I前胶原，在纤维形成过程中进行蛋白水解加工。缺乏编码蛋白质的小鼠在子宫内因主要血管破裂而死亡。表达这个基因显著较低水平的转基因小鼠在矿化和非矿化结缔组织中表现出形态和功能缺陷，并逐渐丧失听力。[RefSeq，2015年11月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Col1a1 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
