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中文小鼠
Col4a1 - collagen, type IV, alpha 1
Alias:
Bru
Raw
Svc
Col4a-1
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这个基因编码IV型胶原蛋白的alpha-1亚基，基底膜的主要成分。编码的蛋白质形成一个由两个alpha-1和一个alpha-2亚基组成的三重螺旋异源三聚体，组装成IV型胶原蛋白网络。这个基因与编码alpha-2亚基的基因相邻。缺乏IV型胶原蛋白的alpha-1和alpha-2亚基的小鼠在子宫内死亡，原因是基底膜的结构缺陷，而此基因中的某些突变导致围产期脑出血和脑出血。这个基因的可变剪接导致多个转录变异体。[RefSeq，2015年11月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Col4a1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
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