人类

EDARADD - EDAR Associated Via Death Domain

Alias:
CR
ED3
EDA3
ECTD11A
ECTD11B
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因是通过与外胚层发育不良相关而被识别的,这是一种以毛发、牙齿和汗腺发育缺陷为特征的遗传性疾病。这个基因编码的蛋白质是一个含有死亡结构域的蛋白质,被发现与EDAR相互作用,EDAR是一个已知对毛发、牙齿和其他外胚层衍生物的发育必需的死亡结构域受体。这个蛋白质和EDAR在毛囊和牙齿形成过程中的上皮细胞中共同表达。通过与其与EDAR的相互作用,这个蛋白质作为适配器,将受体连接到下游的信号传导途径。已经报道了这个基因的两个可变剪接转录变异体,它们编码不同的异构体。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
3
6
136672 bp
24.80
144
6
8
9

EDARADD Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Sequence
Comparison
Al agent
Tutorials
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