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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Cxcr4 - chemokine (C-X-C motif) receptor 4
Alias:
CD184
LESTR
Sdf1r
CXC-R4
CXCR-4
Cmkar4
PB-CKR
b2b220Clo
PBSF/SDF-1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
预测能够实现多种功能,包括化学趋化因子受体活性;细胞骨架蛋白结合活性;以及泛素蛋白连接酶结合活性。参与髓鞘的维护;正调节冷诱导产热;以及正调节少突胶质细胞分化。在几个过程的上游或内部发挥作用,包括循环系统发育;配子生成;以及神经系统发育。位于细胞间连接;质膜外侧;以及生长锥。在几个结构中表达,包括消化系统;心血管系统;胚胎间充质;胚外成分;以及神经系统。用于研究WHIM综合征。该基因的人类同源物与WHIM综合征;血液肿瘤(多种);白细胞减少症;骨质疏松症;以及胰腺癌有关。与人类的CXCR4(C-X-C基序趋化因子受体4)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:12767
ENSEMBL:ENSMUSG00000045382
UNIPROT:P70658
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
12767
4
2
4101 bp
40.43
16
13
Cxcr4 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
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Type
Name
MGI
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References Literature
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