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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Socs1 - suppressor of cytokine signaling 1
Alias:
JAB
Cish1
Cish7
SSI-1
SOCS-1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
激活激酶抑制剂活性。参与CD8阳性,α-β T细胞负调控分化和CD4阳性,α-β T细胞正调控分化。在几个过程的上游或内部发挥作用,包括细胞表面受体信号通路;胰岛素受体信号通路的负调控;以及肽基-酪氨酸磷酸化的调控。预测位于细胞质核糖核蛋白颗粒和核质中。预测是磷脂酰肌醇3-激酶复合物的一部分。在几个结构中表达,包括脂肪组织;肠道;血淋巴系统腺体;神经系统;和生殖系统。这个基因的人类同源物涉及卵巢癌;前列腺癌;和膀胱癌。与人类的SOCS1(细胞因子信号传导抑制子1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:12703
ENSEMBL:ENSMUSG00000038037
UNIPROT:O35716
Basic Information
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Transcripts
Exons
Length
MW (kDa)
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12703
2
2
1729 bp
23.71
12
19
Socs1 Genetics information (-)
GRCm39
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* This data comes from NCBI.
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