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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
CNTF - Ciliary Neurotrophic Factor
Alias:
HCNTF
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Description
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码的蛋白质是一种多肽激素,其作用似乎仅限于神经系统,在那里它促进神经递质的合成和某些神经元群体的神经突生长。这种蛋白质是神经元和大神经元的强力生存因子,可能与减少炎症攻击期间组织破坏有关。这个基因中的突变导致剪接异常,导致睫状神经营养因子缺乏,但这种表型与神经疾病没有因果关系。已经发现了由上游ZFP91基因和CNTF序列组成的读穿转录本变异体,但认为它是非编码的。在小鼠中也观察到了ZFP91和CNTF的读穿转录。[RefSeq,2010年10月提供]
Related ID:
NCBI:1270
ENSEMBL:ENSG00000242689
HGNC:2169
UNIPROT:P26441
OMIM:118945
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1270
1
2
3069 bp
22.93
16
--
8
9
CNTF Genetics information (+)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
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Transcripts & Proteins
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Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Name
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No data available
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CAS Number
Status
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Link
No data available
References Literature
Title
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Journal
Year
IF
No Data Found!
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