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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
人类
CNR1 - Cannabinoid Receptor 1
Alias:
CB1
CNR
CB-R
CB1A
CB1R
CANN6
CB1K5
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码两种大麻素受体之一。大麻素主要是delta-9-四氢大麻酚和合成类似物,它们是大麻的精神活性成分。大麻素受体是鸟嘌呤核苷酸结合蛋白(G蛋白)耦合受体家族的成员,它们以剂量依赖的、立体选择性的和百日咳毒素敏感的方式抑制腺苷酸环化酶活性。已经发现这两个受体涉及大麻素诱导的CNS效应(包括情绪和认知的改变),这是大麻使用者所经历的效果。已经描述了这个基因的多个转录变异体,它们编码两种不同的蛋白质异构体。[RefSeq提供,2009年5月]
Related ID:
NCBI:1268
ENSEMBL:ENSG00000118432
HGNC:2159
UNIPROT:P21554
OMIM:114610
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1268
20
2
27486 bp
52.86
14
--
25
21
CNR1 Genetics information (-)
GRCh38
Sequence Homology
Related Diseases and Mutations
#
Disease
Anatomical Category
Score
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No data available
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
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Alphabetical
Cell-specific RNA expression
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Type
Name
MGI
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Mutations
No data available
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Name
CAS Number
Status
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Link
No data available
References Literature
Title
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Journal
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IF
No Data Found!
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