Log In|Sign Up
中文小鼠
Chek1 - checkpoint kinase 1
Alias:
Chk1
rad27
Favorite
激活组蛋白激酶活性（特异性的H3-T11）。参与在具有转录能力的构象中染色质的表观遗传维持；调控组蛋白H3-K9的乙酰化；以及响应UV诱导的DNA损伤调控从RNA聚合酶II启动子的转录。在几个过程的上游或内部发挥作用，包括DNA损伤检查点信号传导；有丝分裂细胞周期的G2/M过渡；内细胞团细胞增殖。位于染色质；核；和复制叉。在几个结构中表达，包括肾上腺髓质；早期概念体；性腺；肠道；和来自神经嵴的躯干间充质。这个基因的人类同源物与胰腺癌有关。与人类CHEK1（检查点激酶1）正交。[由基因组资源联盟，2022年4月提供]
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
Chek1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
References Literature
Title
PMID
Journal
Year
IF
