Home
Toolbox
Resource
Workflow
Tutorials
Citations
Downloads
Mutation Al-Predictor Flow
Gene-to-Mutation Flow
News & Insights
Genetic Encyclopedia
Frontiers
Industry Insights
Case Studies
About Us
About the Site
Contact Us
Private Policy
User Agreement
COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
Log In
|
Sign Up
中文
小鼠
Cdkn2c - cyclin dependent kinase inhibitor 2C
Alias:
p18
INK4c
p18-INK6
p18INK4c
p18-INK4c
Create a favorites folder
Cancel
Confirm
Add To Favorites
Select a favorites
Description
New favorites >>
Cancel
Confirm
Favorite
Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因编码的蛋白质是周期蛋白依赖的激酶(cdk)抑制剂INK4家族的成员,包含五个ankyrin重复序列。这个蛋白质与Cdk4和Cdk6相互作用,抑制它们的激酶活性,防止它们与D型周期蛋白的相互作用,从而负调控细胞分裂。这个基因在各种组织中的表达存在差异,并且受到细胞周期的调控。这个基因的缺失可能导致肿瘤生长。在G2/M期表达达到最大值。选择性剪接和启动子使用导致多个转录变异体。[RefSeq,2014年8月提供]
Related ID:
NCBI:12580
ENSEMBL:ENSMUSG00000028551
UNIPROT:Q60772
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
12580
2
3
5881 bp
18.07
4
9
Cdkn2c Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
Tissue-specific RNA expression
Organ
Abundance
Alphabetical
Cell-specific RNA expression
Organ
Abundance
Alphabetical
Interactions
Reset
Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available
Related Mouse Models
Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available
References Literature
Title
PMID
Journal
Year
IF
No Data Found!
Wechat
Sequence
Comparison
Al agent
Tutorials
Back to top