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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Cdc45 - cell division cycle 45
Alias:
Cdc45l
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
具有预测的DNA复制起点结合活性;染色质结合活性;以及单链DNA结合活性。参与DNA复制起始;通过断裂诱导复制进行双链断裂修复;有丝分裂DNA复制前期复合物组装。在DNA复制上游或内部发挥作用。位于中心体;鞭毛基体;核质中。是DNA复制前期复合物的一部分。在包括消化系统;鳃弓;心血管系统;中枢神经系统;以及脊索等多个结构中表达。该基因的人类同源物与Meier-Gorlin综合征7有关。与人类CDC45(细胞分裂周期45)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:12544
ENSEMBL:ENSMUSG00000000028
UNIPROT:Q9Z1X9
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
12544
9
20
33170 bp
65.38
4
11
Cdc45 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
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* This data comes from NCBI.
Gene Expression
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Cell-specific RNA expression
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Acting
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Type
Name
MGI
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References Literature
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