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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Ccnd1 - cyclin D1
Alias:
cD1
CycD1
Cyl-1
PRAD1
bcl-1
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
使细胞周期蛋白依赖的蛋白质丝氨酸/苏氨酸激酶调节剂活性正常化;蛋白质激酶活性;和蛋白质激酶结合活性。参与上皮细胞分化的负调控和RNA聚合酶II转录的负调控。在几个过程的上游或内部发挥作用,包括内质网未折叠蛋白响应;腺体发育;和乳腺上皮细胞增殖的正调控。位于双细胞紧密连接;细胞质;和细胞核。是细胞周期蛋白依赖的蛋白质激酶全酶复合物的一部分。在几个结构中表达,包括消化系统;中枢神经系统;生殖泌尿系统;皮肤和感觉器官。该基因的人类同源物涉及几种疾病,包括癌(多种);结直肠癌;血液癌(多种);侵袭性小叶癌;和von Hippel-Lindau病。与人类的CCND1(细胞周期蛋白D1)正交。[由基因组资源联盟,2022年4月提供]
Related ID:
NCBI:12443
ENSEMBL:ENSMUSG00000070348
UNIPROT:P25322
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
12443
2
5
9901 bp
33.43
11
14
Ccnd1 Genetics information (-)
GRCm39
Sequence Homology
Transcripts & Proteins
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#
Transcript
Length(nt)
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CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.
Gene Expression
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Name
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