人类

ACKR2 - Atypical Chemokine Receptor 2

Alias:
D6
hD6
CCR9
CCBP2
CCR10
CMKBR9
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Basic Information
Sequence Homology
Related Diseases and Mutations
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
Related Drugs
References Literature
这个基因编码一个β-趋化因子受体,预测是一个类似于G蛋白偶联受体的七跨膜蛋白。趋化因子及其受体介导的信号传导对于效应免疫细胞招募到炎症部位至关重要。这个基因在一系列组织和造血细胞中表达。这个受体在淋巴内皮细胞中的表达和血管肿瘤中的过度表达提示其在趋化因子驱动的白细胞循环中的作用以及趋化因子对血管肿瘤发展和生长的可能作用。这个受体似乎结合大多数β-趋化因子家族成员,但是其特定功能仍然未知。这个基因定位在染色体3p21.3上,这个区域包含一个趋化因子受体基因簇。[由RefSeq,2008年7月提供]

Basic Information

NCBI
Transcripts
Exons
Length
MW (kDa)
Mutations
Related Diseases
Related Mouse Models
Reference
1
3
57842 bp
43.44
7
--
3
14

ACKR2 Genetics information (+)

GRCh38

Sequence Homology

Related Diseases and Mutations

#
Disease
Anatomical Category
Score
Mutations
No data available

Transcripts & Proteins

Table View
Tile View
#
Transcript
Length(nt)
Exon Count
CDS(bp)
Protein
Length(aa)
No data available
* This data comes from NCBI.

Gene Expression

Tissue-specific RNA expression

Organ
Abundance
Alphabetical

Cell-specific RNA expression

Organ
Abundance
Alphabetical

Interactions

Acting
Regulation
Detail
Mechanism
Target
Residues
Reference
Score
No data available

Related Mouse Models

Type
Name
MGI
Strain of Origin
Publications
Mutations
No data available

Related Drugs

Name
CAS Number
Status
Phase
Link
No data available

References Literature

Title
PMID
Journal
Year
IF
No Data Found!
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Mutation Direct
Sequence
Comparison
Al agent
Tutorials
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