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COL4A5 c.1390G>A
ALS1
DMD c.1332-11868C>G
TP53
肌萎缩侧索硬化症1型
USH2A c.8559-2A>G
囊性纤维化
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中文
小鼠
Casp9 - caspase 9
Alias:
Mch6
APAF-3
CASP-9
ICE-LAP6
Caspase-9
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
这个基因是半胱天冬酶家族的一部分,半胱天冬酶是一种天冬氨酸特异性的半胱氨酸蛋白酶,在免疫和凋亡信号传导方面研究得相当充分。这种蛋白质,即起始半胱天冬酶,在细胞色素c从线粒体释放后被激活,并针对下游效应子。在鼠中,这个基因的缺陷可能导致围产期死亡。这个蛋白质可能在正常大脑发育中发挥作用。可变剪接导致多个转录变异体,它们编码不同的蛋白质异构体。[由RefSeq,2013年4月提供]
Related ID:
NCBI:12371
ENSEMBL:ENSMUSG00000028914
UNIPROT:Q8C3Q9
Basic Information
NCBI
Transcripts
Exons
Length
MW (kDa)
Related Mouse Models
Reference
12371
3
9
22367 bp
49.98
6
4
Casp9 Genetics information (+)
GRCm39
Sequence Homology
Transcripts & Proteins
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* This data comes from NCBI.
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